10 Best Despicable Me 2 Characters, Ranked
If you love Despicable Me 2 for more than the Minions’ latest accident, its characters are probably the reason you keep coming back. The 2013 animated sequel sends Gru on a new mission with Anti-Villain League agent Lucy Wilde, but it also asks how a former supervillain is settling into life as a father. Around him are three daughters with different personalities, a scientist who misses villainy, an outrageous new enemy and a crowd of loyal yellow helpers who are not always as useful as they intend to be.
Gru (Steve Carell) has left his criminal career behind and is raising Margo, Edith and Agnes. When a dangerous mutagen called PX-41 is stolen, the Anti-Villain League recruits him to help identify the culprit. Lucy (Kristen Wiig) becomes his partner, and their investigation leads to Paradise Mall, where restaurant owner Eduardo Pérez (Benjamin Bratt) attracts Gru’s suspicion. As the case unfolds, Gru must protect his family and the Minions while deciding whether he is ready to let someone new into his life.
Directors Chris Renaud and Pierre Coffin give the sequel room for family comedy, romantic awkwardness and a colourful spy adventure. The characters make those ingredients work together. Agnes can turn Gru’s fear of change into a direct question; Margo reminds him that his children are growing up; and Lucy challenges him without expecting him to abandon the family he already loves.
For this ranking, we are judging the characters by their contribution toDespicable Me 2, rather than by everything they do elsewhere in the franchise. We consider their role in the story, relationships, humour, emotional impact and how much they add on a rewatch. The Minions are treated as one ensemble because the film often uses them as a group, even though individual Minions have distinct moments. This is a subjective countdown from number 10 to number 1.
Spoiler warning:The list discusses the villain’s identity, the Minions’ transformation and the ending. UK viewing options can change; check the current film listingbefore planning your next family movie night. Let’s get into it
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10. Silas Ramsbottom

Image source: IMDb · Image credit: Illumination / Universal Pictures
Silas Ramsbottom (voiced by Steve Coogan) leads the Anti-Villain League, the organisation trying to recover the stolen PX-41 mutagen. He needs someone who understands how a supervillain might hide and use the chemical, so Lucy brings Gru to him. Silas offers the retired criminal a chance to work on the other side of the law, putting him on a mission that will take him to Paradise Mall and into the path of Eduardo Pérez. Gru’s knowledge is useful, but Silas still has to decide whether a former villain can be trusted.
The character gives the sequel a doorway into its spy-story world. Without Silas and the league, Gru could remain at home making jelly and attending birthday parties. The organisation creates a reason for him to use his old skills again, while the relationship with Lucy gives the assignment a personal dimension that neither Gru nor Silas initially expects.
Coogan gives Silas a brisk official manner that contrasts nicely with the Minions’ reaction to his name. He is attempting to explain a serious threat while the little yellow helpers find another reason to laugh. The joke is simple, but it establishes how difficult it can be to bring formal authority into Gru’s chaotic orbit.
Silas is not as emotionally developed as the central family. His choices are mainly tied to the investigation, and the film has less time to show his life beyond the agency. That narrower role is appropriate for a supporting character, but it limits how much of the film’s emotional payoff belongs to him.
Why he ranks here:Silas earns tenth because he sets the mission in motion and provides a useful comic contrast to the Minions. He stays below the other characters because his relationships and personal story receive less attention.
Best for:Viewers who enjoy the Anti-Villain League’s spy-movie setting and dry authority figures.
Where to watch:Check Despicable Me 2’s current UK listing.
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9. Jillian

Image source: Fandom · Image credit: Illumination / Universal Pictures
Jillian (voiced by Nasim Pedrad) is a neighbour who takes an enthusiastic interest in Gru’s personal life. Now that he is raising three daughters on his own, she is convinced he should meet someone and repeatedly offers to arrange a date. Gru is uncomfortable with her attention and does not know how to refuse without becoming trapped in another conversation. Her matchmaking eventually leads to an awkward evening with Shannon, where Lucy unexpectedly helps him escape a humiliating situation.
Jillian is funny because her confidence leaves very little room for Gru’s reluctance. She appears to believe that finding him a partner is a practical problem she can solve if she simply keeps presenting candidates. Gru, who once planned elaborate crimes, has trouble navigating the ordinary social pressure of a neighbour who will not take a hint.
Her role also reveals a question the sequel is asking from several directions: does Gru want another adult in his life, and if he does, what kind of relationship would work for him and his daughters? Jillian cannot answer that by choosing a date on his behalf. The failed arrangement makes the contrast with Lucy clearer, because Lucy notices Gru’s discomfort instead of expecting him to perform confidence.
The joke can be broad, and Jillian is largely defined by her matchmaking rather than a fully developed life of her own. Still, Pedrad’s energetic performance makes her brief appearances useful to the film’s rhythm. She creates a problem that feels domestic and recognisable even in a story full of secret weapons.
Why she ranks here:Jillian places ninth because her determined matchmaking brings out Gru’s social awkwardness and helps set up an important Lucy scene. She edges above Silas for the personal comedy she creates, but her limited screen time keeps her below the family members and allies ahead.
Best for:Viewers who enjoy awkward-neighbour comedy and characters who mistake persistence for tact.
Where to watch:See the film’s UK streaming and rental options.
8. Edith

Image source: IMDb · Image credit: Illumination / Universal Pictures
Edith (voiced by Dana Gaier) is Gru’s middle daughter, living with her sisters Margo and Agnes as their adopted father adjusts to a life away from supervillainy. She brings a mischievous streak to the household and enjoys the excitement surrounding Gru’s gadgets, Minions and unusual work. When the family’s world becomes dangerous again, Edith is part of the group that cares about Gru’s missing helpers and supports the effort to bring them back.
Edith’s personality helps the sisters feel like three distinct people rather than a single unit. Margo is the eldest and begins exploring a romantic interest; Agnes is more openly hopeful about finding someone for Gru; Edith often supplies the adventurous energy between them. She can be cheeky and fearless without needing to behave exactly like her father.
Her presence also makes Gru’s home life feel busy in a believable cartoon way. A family gathering is not only about the adults explaining the plot. Each daughter can react differently to a party, a visitor or a new relationship, and Edith’s appetite for mischief gives scenes another rhythm. Gaier’s voice performance helps communicate that confidence in relatively brief moments.
The sequel does not give Edith as much individual development as Margo’s relationship with Antonio or Agnes’s wish for a mother. That is a limitation of the film’s crowded story rather than a reason to overlook her. She contributes to the family dynamic, but viewers wanting a substantial Edith-centred arc will find less material here than they might expect.
Why she ranks here:Edith takes eighth because her mischievous energy strengthens the household and distinguishes her from her sisters. She outranks Jillian for her continuing place in Gru’s family, while her smaller individual storyline keeps her below the characters with more decisive roles.
Best for:Fans who like adventurous, cheeky characters and the sisters’ contrasting personalities.
Where to watch:Check Despicable Me 2 on JustWatch UK.
7. Dr Nefario

Image source: Wallpaper Abyss · Image credit: Illumination / Universal Pictures
Dr Nefario (voiced by Russell Brand) has spent years inventing gadgets and helping Gru carry out ambitious schemes. In the sequel, Gru has retired from villainy and is trying to run a legitimate jelly business, leaving Nefario dissatisfied with his quieter work. He accepts another opportunity and leaves Gru’s household, but his new position brings him close to Eduardo’s dangerous plans. When the Minions are transformed by PX-41 and Lucy is threatened, Nefario’s choices and scientific abilities become important to the effort to put things right.
Nefario is more interesting than a collection of inventions because he has his own preference for excitement. Gru’s decision to become a father is right for Gru, but it does not automatically give his old colleague a satisfying new purpose. Their separation shows that changing a life can affect the people who helped build it, even when nobody is trying to hurt anyone.
The Minions’ noisy farewell gives that change a comic shape. Their salute is deliberately ridiculous, yet it communicates affection for a colleague who has long been part of their group. Nefario’s relationship with them becomes more significant once he sees what PX-41 has done to captured Minions.
His development of an antidote gives him a concrete role in the climax. Rather than simply producing another weapon, he helps find a way to restore the creatures Gru wants to save. The science is cartoonishly convenient, but the choice fits a character whose skills can be used for different purposes depending on the person he chooses to assist.
Why he ranks here:Nefario reaches seventh because his departure and return affect both the story and the Minions’ fate. He beats Edith for his decisive contribution to the climax, but the higher-ranked characters have either stronger emotional arcs or a greater presence throughout the film.
Best for:Viewers who enjoy eccentric inventors and supporting characters whose loyalty is tested.
Where to watch:Find current UK viewing options.
6. Eduardo Pérez / El Macho

Image source: IMDb · Image credit: Illumination / Universal Pictures
Eduardo Pérez (voiced by Benjamin Bratt) presents himself as the friendly owner of Salsa & Salsa at Paradise Mall. He is also the father of Antonio, the boy who attracts Margo’s attention. Gru, investigating the theft of PX-41, suspects that Eduardo is actually El Macho, a flamboyant supervillain believed to be dead. Beneath the restaurant-owner persona, Eduardo has taken the mutagen and is transforming captured Minions into purple creatures for a plan that threatens far more than the shopping centre.
Eduardo gives Gru two different reasons to feel uneasy. As an investigator, Gru recognises signs that his apparently welcoming host may be hiding something. As a father, he is uncomfortable with Margo’s interest in Antonio. The overlap means that a party at Eduardo’s home can be both an undercover opportunity and a deeply awkward family occasion.
Bratt’s performance gives the villain a confident, theatrical charm. Eduardo enjoys presenting himself as generous and larger than life, which makes his true identity feel like an extension of his personality rather than an entirely separate disguise. His stories of spectacular villainy belong in the same exaggerated world as Gru’s moon-stealing past.
The purple Minion plan also makes the conflict personal. Eduardo is not merely pursuing an abstract goal of world domination; he is using creatures who have been loyal to Gru and familiar to the audience. That gives Gru a reason to search for a cure as well as stop the scheme.
El Macho is entertaining, though his motivation is comparatively straightforward. The film spends more emotional time on Gru, Lucy and the girls than on explaining why Eduardo wants power. That keeps the adventure moving but gives him less depth than the strongest characters in this countdown.
Why he ranks here:Eduardo takes sixth for his dual identity, comic confidence and central threat to the Minions. He rises above Nefario for driving the main conflict, but he misses the top five because his relationships and motives are less developed than those of Gru’s family and allies.
Best for:Fans of flamboyant animated villains and secret identities.
Where to watch:Check the UK film listing.
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5. Margo

Image source: IMDb · Image credit: Illumination / Universal Pictures
Margo (voiced by Miranda Cosgrove) is Gru’s eldest daughter and often the most visibly protective of her younger sisters. In Despicable Me 2, she is also beginning to develop interests that Gru cannot manage for her. When she meets Eduardo’s son Antonio, she enjoys his attention and wants the freedom to explore a romance. Gru’s suspicion of Eduardo and his anxiety about Margo growing up make the situation more complicated, especially when the family attends Eduardo’s party.
Margo’s story matters because it shows that becoming a family did not freeze the three girls at the age they were when Gru adopted them. She can care about her sisters and still want experiences of her own. Gru loves her, but loving a child does not make it easy to accept that she will make decisions and face disappointments he cannot prevent.
When Antonio’s behaviour hurts Margo, her reaction gives the party sequence an emotional centre. Gru’s protective response is exaggerated for comedy, yet it follows a recognisable parental impulse: he wants to spare her pain and does not have a normal way to reverse what has happened. Margo’s feelings give the gadget joke its context.
Cosgrove’s performance keeps Margo grounded among characters whose reactions are often much louder. She can be enthusiastic, embarrassed or frustrated without becoming a miniature version of Gru. Her independence also helps the audience see him from another angle: the father who would do anything for his daughters must learn that support is not the same as control.
The film could give Margo even more space beyond the Antonio storyline, and her sisters’ roles sometimes have to compete with the spy plot. Still, her changing relationship with Gru is one of the sequel’s clearest signs that the family is continuing to grow.
Why she ranks here:Margo opens the top five because her wish for independence gives Gru’s fatherhood story a meaningful new challenge. She beats Eduardo for emotional depth, though the four characters above are more central to the film’s overall structure or comic identity.
Best for:Viewers who appreciate parent-child stories about growing independence.
Where to watch:See Despicable Me 2’s UK availability.
4. Agnes

Image source: IMDb · Image credit: Illumination / Universal Pictures
Agnes (voiced by Elsie Fisher) is Gru’s youngest daughter, whose enthusiasm and directness often reveal what the family is feeling before anyone else says it aloud. She enjoys the security of her home with Gru, Margo and Edith, but she also hopes that Gru might find someone who could become part of their family. Her birthday party, questions about a mother and response to Lucy give the sequel’s romantic plot a family perspective: Gru is not the only person affected by the possibility of a new relationship.
Agnes is easy to describe as adorable, but her role is more specific than a collection of cute reactions. She asks for things plainly. When the planned princess entertainer is unavailable, Gru’s decision to improvise matters because Agnes’s happiness is a real priority for him. Her expectations reveal how much his daily life has changed since the first film.
Her wish for a mother also creates a delicate emotional question. Gru is already a loving parent, and the film does not need to treat him as inadequate in order to acknowledge Agnes’s hope. Lucy’s arrival offers the possibility of another bond, not a replacement for the one Agnes already has with her father and sisters.
Fisher’s performance gives Agnes’s excitement an immediacy that suits the film’s visual comedy. She can be delighted by a celebration or sincere about a family wish without sounding as though she is delivering a lesson. The character helps the sequel move between jokes and affection because her feelings are clear even when the situation around her is absurd.
Agnes has less control over the central mission than Lucy or Gru, and the film’s adult romance is not entirely hers to resolve. Her contribution is nevertheless substantial: she makes the potential family change visible from the perspective of someone who will live with it.
Why she ranks here:Agnes takes fourth for the warmth and clarity she brings to Gru’s family story. She edges above Margo because her hopes connect directly to the film’s ending, but the top three shape more of the adventure and its comedy.
Best for:Families who enjoy a character whose enthusiasm gives the story its emotional heart.
Where to watch:Check current UK streaming and rental options.
3. The Minions

Image source: Filmtekercs · Image credit: Illumination / Universal Pictures
Gru’s Minions are his loyal yellow helpers, working in the laboratory and following him from supervillainy into a more domestic life. In Despicable Me 2, they assist with the jelly business, create chaos during Gru and Lucy’s investigation and give Dr Nefario a spectacularly noisy farewell. Their loyalty becomes a source of danger when Eduardo captures many of them and uses PX-41 to turn them into aggressive purple creatures. Gru and his allies must stop El Macho’s plan while finding a way to restore the Minions themselves.
We are ranking them as an ensemble rather than pretending that every Minion has the same personality. The film often uses the group as a comic force, with individual helpers contributing to a larger routine. Their language, reactions and willingness to turn a simple instruction into a complicated event give the sequel a physical-comedy rhythm that does not depend on lengthy dialogue.
The mall rescue is a good example. Gru and Lucy need to escape after investigating Eduardo’s restaurant, and two Minions arrive with a vehicle. Their aim is loyal and helpful, but the execution is so chaotic that the rescue becomes another problem for the agents. The audience can understand both intentions at once: the Minions are trying to do the right thing and are spectacularly bad at keeping it simple.
The purple transformation changes their role from comic assistants to people—or creatures—the family needs to save. Their familiar appearance is part of the audience’s attachment, so seeing them altered creates concern beneath the exaggerated action. The antidote is satisfying because it restores companions rather than merely removing obstacles.
Pierre Coffin voices the Minions, with Chris Renaud also credited for additional Minion voices. Their vocal performance and animation work together: tone, movement and timing communicate enthusiasm or confusion even when the words are not conventional English. Not every gag will work equally well for every viewer, and a heavy dose of Minion noise can compete with the more intimate family story.
Why they rank here:The Minions take third because they contribute some of the film’s strongest physical comedy and become central to its main danger. They sit above Agnes for their broader role in the adventure, but below Lucy and Gru because the sequel’s most developed emotional choices belong to those two characters.
Best for:Viewers who love visual slapstick, cheerful chaos and loyal helpers with questionable judgement.
Where to watch:Check Despicable Me 2 on JustWatch UK.
2. Lucy Wilde

Image source: CultureMap Dallas · Image credit: Illumination / Universal Pictures
Lucy Wilde (voiced by Kristen Wiig) is an Anti-Villain League agent assigned to recruit Gru after a dangerous chemical is stolen. She arrives with an upbeat manner, a lipstick taser and a willingness to treat the former supervillain as someone whose expertise could help. The pair go undercover at Paradise Mall, where they investigate possible suspects and gradually learn to trust one another. When Lucy is reassigned to Australia, both have to confront the possibility that their partnership means more than either has said.
Lucy is an excellent addition because she has a life and job before becoming Gru’s romantic interest. She initiates the recruitment, contributes gadgets and ideas to the investigation and acts when a situation turns dangerous. Her energy can overwhelm Gru, but it also invites him to use skills he thought belonged only to his old life.
Their chemistry grows through action and small acts of consideration. At the restaurant, Lucy sees that Gru’s date with Shannon has become humiliating and helps him. During the investigation, she responds to his suspicions rather than simply dismissing his experience. Gru is accustomed to protecting his daughters and managing his helpers; Lucy gives him a relationship in which someone can also look out for him.
Wiig’s performance makes Lucy’s enthusiasm distinctive. She can sound delighted by a gadget or an undercover assignment without losing the sense that she is capable. The comic energy is important, but the character also needs to feel like someone who could fit into a household containing three daughters, a scientist and a crowd of Minions. Her openness makes that possibility plausible.
Lucy has agency in the final act too. She turns back because she recognises her feelings for Gru, even though El Macho captures her before they can reunite. The subsequent rescue places her in danger, but it follows a choice she has made rather than a passive wait for the plot to reach her.
The film moves quickly from their adventure to a wedding, so viewers who want a longer courtship may feel the ending compresses their relationship. Still, the sequel gives Lucy enough independent action and warmth to make her more than a solution to Gru’s loneliness.
Why she ranks here:Lucy earns second for driving the mission, matching Gru’s comic energy and creating the sequel’s most important new relationship. She narrowly misses first because Gru’s decisions connect the spy plot, the Minions and all three daughters more completely.
Best for:Fans of energetic agents, gadget comedy and a romance built through teamwork.
Where to watch:See the current UK listing.
1. Gru

Image source: Wallpaper Abyss · Image credit: Illumination / Universal Pictures
Gru (voiced by Steve Carell) begins Despicable Me 2 as a retired supervillain trying to build a stable life for Margo, Edith and Agnes. He runs a jelly business with Dr Nefario and the Minions, deals with birthday parties and resists his neighbour’s attempts to arrange a date. When Lucy recruits him for the Anti-Villain League, Gru faces a new challenge: use the knowledge and instincts of his old criminal life to stop a villain while remaining the father his daughters need.
That situation makes him the sequel’s strongest character because every major story passes through a choice he must make. He can accept or refuse the agency’s mission, trust or distrust Lucy, confront his suspicion of Eduardo and decide how to respond when Margo wants more independence. None of those problems has exactly the same solution, even though Gru’s instinct is often to take control.
Carell’s voice performance preserves the character’s comic confidence while allowing anxiety and affection to come through. Gru can announce a gadget with great seriousness, then become completely uncomfortable at a restaurant date. The humour does not require him to stop being the person audiences met in the first film. Instead, the sequel puts familiar traits into situations where a grand villainous plan will not necessarily help.
His relationship with the girls is the foundation. At Agnes’s party, he is willing to look ridiculous because she matters more than his pride. With Margo, he has to face a harder part of parenting: she can be hurt, and he cannot make every decision for her. Edith’s mischievous presence and the family’s everyday routines remind him that the home he built is active and changing, not a reward he can simply place on a shelf.
Lucy challenges him in a different way. She appreciates his abilities, works alongside him and helps when he is embarrassed, but Gru has to decide whether he will risk expressing his own feelings. Her possible departure makes that decision urgent. Their relationship works because it grows alongside his existing responsibilities rather than requiring him to abandon them.
Gru’s loyalty to the Minions completes the picture. When they are transformed, he needs a way to stop the threat and save his helpers. The antidote turns the climax into an act of recovery as well as a fight against El Macho. Gru’s former world of inventions and schemes remains useful, but his goal has changed.
The wedding at the end moves quickly through the couple’s courtship, and the film occasionally gives supporting characters less space so that Gru’s story can remain central. Those choices do not erase the strength of his arc. He is funniest when his dignity fails him and most affecting when he accepts that caring for people means allowing them to change his plans.
Why he ranks first:Gru connects the sequel’s family, romance, comedy and spy adventure more fully than anyone else. He edges out Lucy because his choices affect all three daughters, the Minions and the mission, while Carell’s performance makes his awkwardness and affection equally memorable.
Best for:Anyone who wants the film’s most complete mix of character growth, family comedy and animated adventure.
Where to watch:Confirm Despicable Me 2’s current UK availability.
What Makes the Cast Work Together?
The sequel does not rely on Gru being funny in isolation. Lucy’s enthusiasm exposes his reluctance, the Minions turn his instructions into physical comedy, and the girls give him reasons to care about outcomes beyond his own reputation. Each relationship draws out a different side of him.
The supporting cast also makes the story move. Silas creates the mission, Jillian creates social pressure, Eduardo provides a threat and Nefario helps repair the damage. Not all receive equal development, but their roles give the central family a range of problems to solve.
The most effective characters combine clear comic identities with understandable wants. Agnes wants a happy family, Margo wants independence, Lucy wants to do her job and connect with Gru, and the Minions want to help their boss. Those goals make the exaggerated action easy to follow.
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Final Thoughts
Despicable Me 2 works because its spy adventure grows around a family that has already changed its former villain. Lucy’s arrival gives Gru a new partner, Eduardo makes the mission dangerous, and the Minions turn loyalty into both comedy and a problem that needs solving.
Gru takes our number one spot for connecting those stories, with Lucy close behind as the sequel’s most valuable new character. Agnes, Margo, Edith and the rest of the cast give the household its own variety of voices. Who would be your number one?
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Frequently Asked Questions
Who is the best Despicable Me 2 character?
Our number one is Gru because his choices connect the family story, Lucy’s partnership, the Minions and the Anti-Villain League mission.
Who voices Gru and Lucy?
Steve Carell voices Gru, and Kristen Wiig voices Anti-Villain League agent Lucy Wilde.
Who are Gru’s daughters?
Margo, Edith and Agnes are the sisters Gru adopted in the first film. Miranda Cosgrove, Dana Gaier and Elsie Fisher voice them respectively in Despicable Me 2.
Who is the villain in Despicable Me 2?
Eduardo Pérez is revealed to be El Macho, a supposedly dead supervillain who uses the stolen PX-41 mutagen in his plan. Benjamin Bratt voices him.
Why do the Minions turn purple?
Eduardo uses PX-41 on captured Minions, transforming them into aggressive purple creatures. Gru and his allies work to cure them.
Who voices the Minions?
Pierre Coffin is credited with Minion voices, and Chris Renaud is also credited with additional Minion voices in the film.
Why does Dr Nefario leave Gru?
Nefario misses the excitement of villainous work and accepts another opportunity. His later choices help Gru address the threat facing the Minions.
What does Lucy do for the Anti-Villain League?
Lucy is an agent who recruits Gru and works undercover with him to investigate the stolen mutagen and possible suspects at Paradise Mall.
Where can I watch Despicable Me 2 in the UK?
JustWatch lists Sky Go, NOW Cinema and digital rental or purchase options. Availability can change, so check the current listing.
Is Despicable Me 2 suitable for young children?
The film has a U rating in the UK listing, though the purple Minions and some action scenes may frighten sensitive younger viewers. Check a current parent guide if needed.
Sources and Viewing
Universal Pictures: Despicable Me 2 synopsis and cast
Illumination: Despicable Me 2 characters
Metacritic: Despicable Me 2 voice cast and crew
JustWatch: Despicable Me 2 in the UK
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